116 research outputs found
Extracting novel facts from tables for Knowledge Graph completion
We propose a new end-to-end method for extending a Knowledge Graph (KG) from tables. Existing techniques tend to interpret tables by focusing on information that is already in the KG, and therefore tend to extract many redundant facts. Our method aims to find more novel facts. We introduce a new technique for table interpretation based on a scalable graphical model using entity similarities. Our method further disambiguates cell values using KG embeddings as additional ranking method. Other distinctive features are the lack of assumptions about the underlying KG and the enabling of a fine-grained tuning of the precision/recall trade-off of extracted facts. Our experiments show that our approach has a higher recall during the interpretation process than the state-of-the-art, and is more resistant against the bias observed in extracting mostly redundant facts since it produces more novel extractions
Value at Risk models with long memory features and their economic performance
We study alternative dynamics for Value at Risk (VaR) that incorporate a slow moving component and information on recent aggregate returns in established quantile (auto) regression models. These models are compared on their economic performance, and also on metrics of first-order importance such as violation ratios. By better economic performance, we mean that changes in the VaR forecasts should have a lower variance to reduce transaction costs and should lead to lower exceedance sizes without raising the average level of the VaR. We find that, in combination with a targeted estimation strategy, our proposed models lead to improved performance in both statistical and economic terms
QuerioCity: A Linked Data Platform for Urban Information Management
Abstract. In this paper, we present QuerioCity, a platform to catalog, index and query highly heterogenous information coming from complex systems, such as cities. A series of challenges are identified: namely, the heterogeneity of the domain and the lack of a common model, the vol-ume of information and the number of data sets, the requirement for a low entry threshold to the system, the diversity of the input data, in terms of format, syntax and update frequency (streams vs static data), and the sensitivity of the information. We propose an approach for incre-mental and continuous integration of static and streaming data, based on Semantic Web technologies. The proposed system is unique in the literature in terms of handling of multiple integrations of available data sets in combination with flexible provenance tracking, privacy protection and continuous integration of streams. We report on lessons learnt from building the first prototype for Dublin.
Paternal mtDNA and Maleness Are Co-Inherited but Not Causally Linked in Mytilid Mussels
BACKGROUND: In marine mussels of the genus Mytilus there are two mitochondrial genomes. One is transmitted through the female parent, which is the normal transmission route in animals, and the other is transmitted through the male parent which is an unusual phenomenon. In males the germ cell line is dominated by the paternal mitochondrial genome and the somatic cell line by the maternal. Research to date has not allowed a clear answer to the question of whether inheritance of the paternal genome is causally related to maleness. METHODOLOGY/PRINCIPAL FINDINGS: Here we present results from hybrid crosses, from triploid mussels and from observations of sperm mitochondria in fertilized eggs which clearly show that maleness and presence of the paternal mitochondrial genome can be decoupled. These same results show that the female mussel has exclusive control of whether her progeny will inherit the mitochondrial genome of the male parent. CONCLUSIONS/SIGNIFICANCE: These findings are important in our efforts to understand the mechanistic basis of this unusual mode of mitochondrial DNA inheritance that is common among bivalves
Data Integration for Open Data on the Web
In this lecture we will discuss and introduce challenges of
integrating openly available Web data and how to solve them. Firstly,
while we will address this topic from the viewpoint of Semantic Web
research, not all data is readily available as RDF or Linked Data, so
we will give an introduction to different data formats prevalent on the
Web, namely, standard formats for publishing and exchanging tabular,
tree-shaped, and graph data. Secondly, not all Open Data is really completely
open, so we will discuss and address issues around licences, terms
of usage associated with Open Data, as well as documentation of data
provenance. Thirdly, we will discuss issues connected with (meta-)data
quality issues associated with Open Data on the Web and how Semantic
Web techniques and vocabularies can be used to describe and remedy
them. Fourth, we will address issues about searchability and integration
of Open Data and discuss in how far semantic search can help to overcome
these. We close with briefly summarizing further issues not covered
explicitly herein, such as multi-linguality, temporal aspects (archiving,
evolution, temporal querying), as well as how/whether OWL and RDFS
reasoning on top of integrated open data could be help
Healthcare professionals’ views on patient-centered care in hospitals
Background: Patient-centered care (PCC) is a main determinant of care quality. Research has shown that PCC is a multi-dimensional concept, and organizations that provide PCC well report better patient and organizational outcomes. However, little is known about the relative importance of PCC dimensions. The aim of this study was therefore to investigate the relative importance of the eight dimensions of PCC according to hospital-based healthcare professionals, and examine whether their viewpoints are determined by context. Methods: Thirty-four healthcare professionals (16 from the geriatrics department, 15 from a surgical intensive care unit, 3 quality employees) working at a large teaching hospital in New York City were interviewed using Q methodology. Participants were asked to rank 35 statements representing eight dimensions of PCC extracted from the literature: patient preferences, physical comfort, coordination of care, emotional support, acce
Evidence for a Fourteenth mtDNA-Encoded Protein in the Female-Transmitted mtDNA of Marine Mussels (Bivalvia: Mytilidae)
BACKGROUND: A novel feature for animal mitochondrial genomes has been recently established: i.e., the presence of additional, lineage-specific, mtDNA-encoded proteins with functional significance. This feature has been observed in freshwater mussels with doubly uniparental inheritance of mtDNA (DUI). The latter unique system of mtDNA transmission, which also exists in some marine mussels and marine clams, is characterized by one mt genome inherited from the female parent (F mtDNA) and one mt genome inherited from the male parent (M mtDNA). In freshwater mussels, the novel mtDNA-encoded proteins have been shown to be mt genome-specific (i.e., one novel protein for F genomes and one novel protein for M genomes). It has been hypothesized that these novel, F- and M-specific, mtDNA-encoded proteins (and/or other F- and/or M-specific mtDNA sequences) could be responsible for the different modes of mtDNA transmission in bivalves but this remains to be demonstrated. METHODOLOGY/PRINCIPAL FINDINGS: We investigated all complete (or nearly complete) female- and male-transmitted marine mussel mtDNAs previously sequenced for the presence of ORFs that could have functional importance in these bivalves. Our results confirm the presence of a novel F genome-specific mt ORF, of significant length (>100aa) and located in the control region, that most likely has functional significance in marine mussels. The identification of this ORF in five Mytilus species suggests that it has been maintained in the mytilid lineage (subfamily Mytilinae) for ∼13 million years. Furthermore, this ORF likely has a homologue in the F mt genome of Musculista senhousia, a DUI-containing mytilid species in the subfamily Crenellinae. We present evidence supporting the functionality of this F-specific ORF at the transcriptional, amino acid and nucleotide levels. CONCLUSIONS/SIGNIFICANCE: Our results offer support for the hypothesis that "novel F genome-specific mitochondrial genes" are involved in key biological functions in bivalve species with DUI
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